1642-1807: The slave trade out of Lisbon experienced a period of decline after 1641 following the separation of the Portuguese and Spanish monarchies.

1642-1807: The slave trade out of Lisbon experienced a period of decline after 1641 following the separation of the Portuguese and Spanish monarchies. This political shift closed the previously accessible markets of Spanish America to Portuguese merchants. In response, the trade focused on a steady supply to various regions of Brazil. After 1750, Lisbon merchants pioneered a new triangular route that specifically linked the port with Senegambia in Africa and Amazonia in South America.